@article{468a45c2f342488bbff8ed4557aaa09d,
title = "Real-Time Biosensor Platform Based on Novel Sandwich Graphdiyne for Ultrasensitive Detection of Tumor Marker",
abstract = "Realization of a highly sensitive analysis and sensing platform is important for early-stage tumor diagnosis. In this work, a self-powered biosensor with a novel sandwich graphdiyne (SGDY) combined with an aptamer-specific recognition function was developed to sensitively and accurately detect tumor markers. Results indicated that the detection limits of microRNA (miRNA)-21 and miRNA-141 were 0.15 and 0.30 fM (S/N = 3) in the linear range of 0.05–10000 and 1–10000 fM, respectively. The newly designed platform has great promise for early-stage tumor diagnosis.",
author = "Jing Xu and Yinbing Liu and Ke-Jing Huang and Yang-Yang Hou and Xiaoxuan Sun and Jiaqiang Li",
note = "KAUST Repository Item: Exported on 2022-12-01 Acknowledgements: The authors acknowledge financial support from the Talent Introduction Start-Up Foundation of Guangxi Minzu University (2021KJQD08), Natural Science Foundation of China (No. 22074130). The authors acknowledge the support from the Analysis Testing Center of Xinyang Normal University for the materials characterization.",
year = "2022",
month = nov,
day = "29",
doi = "10.1021/acs.analchem.2c04278",
language = "English (US)",
journal = "Analytical Chemistry",
issn = "0003-2700",
publisher = "American Chemical Society",
}