@inproceedings{da582ed79f064e38a2e164e6f382eb57,
title = "Real-time monitoring of tumour spheroid swelling under transient hypoxia using two-photon microscopy",
abstract = "We present, for the first time, real-time tracking of individual cells within 3D tumour spheroids exhibiting cyclic swelling behaviour in response to time-varying oxygen profiles. Cells and spheroids appear to reversibly swell under 0% O2. This observation was enabled by combining a microfluidic oxygen control device with two-photon microscopy (TPM) to monitor the multicellular spheroids.",
keywords = "3D cell culture, Microfluidics, Spheroid swelling, Transient/cycling hypoxia",
author = "Grist, {S. M.} and L. Laplatine and Nasseri, {S. S.} and A. Diaz-Gaxiola and Liu, {M. C.A.} and L. Chrostowski and Cheung, {K. C.}",
year = "2016",
language = "English (US)",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "51--52",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}