In the past few years, research on the fabrication of deep eutectic solvents (DESs)-based supported liquid membranes (SLMs) is increasing tremendously due to their significant advantages such as low mass transport resistance, high performance, easy scale-up, low cost and simple operation. However, fabrication of DES-based SLMs is challenging and highly dependent on the fabrication parameters: DES properties and properties of membrane supports. Subsequently, the fabrication methods, immersion, pressure-based impregnation and vacuum filtration also affect the permeation performance of DES-based SLMs in liquids and gases separation. Furthermore, the SLM durability is influenced by the DES properties and process parameters including: temperature, pressure, and feed composition. Firstly, present work reviews the current progress and fabrication of DES-based SLMs. Subsequently, it presents a perspective on different strategies that use DESs as a unique tunable platform to design advanced SLMs for liquids and gases separation reported in the literature. In the next step, performances of the SLMs membranes for liquids and gases separation are described in details. The effects of process parameters on DES-based SLMs are also highlighted prior to the challenges. Lastly, challenges and future research opportunities are highlighted.