Receptor kinase module targets PIN-dependent auxin transport during canalization

Jakub Hajný; Tomáš Prát; Nikola Rydza; Lesia Rodriguez; Shutang Tan; Inge Verstraeten; David Domjan; Ewa Mazur; Elwira Smakowska-Luzan; Wouter Smet; Eliana Mor; Jonah Nolf; Bao Jun Yang; Wim Grunewald; Gergely Molnár; Youssef Belkhadir; Bert De Rybel; Jiří Friml

doi:10.1126/SCIENCE.ABA3178

Receptor kinase module targets PIN-dependent auxin transport during canalization

Jakub Hajný, Tomáš Prát, Nikola Rydza, Lesia Rodriguez, Shutang Tan, Inge Verstraeten, David Domjan, Ewa Mazur, Elwira Smakowska-Luzan, Wouter Smet, Eliana Mor, Jonah Nolf, Bao Jun Yang, Wim Grunewald, Gergely Molnár, Youssef Belkhadir, Bert De Rybel, Jiří Friml

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54 Scopus citations

Abstract

Spontaneously arising channels that transport the phytohormone auxin provide positional cues for selforganizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.

Original language	English (US)
Pages (from-to)	550-557
Number of pages	8
Journal	SCIENCE
Volume	370
Issue number	6516
DOIs	https://doi.org/10.1126/SCIENCE.ABA3178
State	Published - Oct 30 2020

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Hajný, J., Prát, T., Rydza, N., Rodriguez, L., Tan, S., Verstraeten, I., Domjan, D., Mazur, E., Smakowska-Luzan, E., Smet, W., Mor, E., Nolf, J., Yang, B. J., Grunewald, W., Molnár, G., Belkhadir, Y., De Rybel, B., & Friml, J. (2020). Receptor kinase module targets PIN-dependent auxin transport during canalization. SCIENCE, 370(6516), 550-557. https://doi.org/10.1126/SCIENCE.ABA3178

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title = "Receptor kinase module targets PIN-dependent auxin transport during canalization",

abstract = "Spontaneously arising channels that transport the phytohormone auxin provide positional cues for selforganizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.",

author = "Jakub Hajn{\'y} and Tom{\'a}{\v s} Pr{\'a}t and Nikola Rydza and Lesia Rodriguez and Shutang Tan and Inge Verstraeten and David Domjan and Ewa Mazur and Elwira Smakowska-Luzan and Wouter Smet and Eliana Mor and Jonah Nolf and Yang, {Bao Jun} and Wim Grunewald and Gergely Moln{\'a}r and Youssef Belkhadir and {De Rybel}, Bert and Ji{\v r}{\'i} Friml",

note = "Generated from Scopus record by KAUST IRTS on 2023-10-23",

year = "2020",

month = oct,

day = "30",

doi = "10.1126/SCIENCE.ABA3178",

language = "English (US)",

volume = "370",

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Hajný, J, Prát, T, Rydza, N, Rodriguez, L, Tan, S, Verstraeten, I, Domjan, D, Mazur, E, Smakowska-Luzan, E, Smet, W, Mor, E, Nolf, J, Yang, BJ, Grunewald, W, Molnár, G, Belkhadir, Y, De Rybel, B & Friml, J 2020, 'Receptor kinase module targets PIN-dependent auxin transport during canalization', SCIENCE, vol. 370, no. 6516, pp. 550-557. https://doi.org/10.1126/SCIENCE.ABA3178

TY - JOUR

T1 - Receptor kinase module targets PIN-dependent auxin transport during canalization

AU - Hajný, Jakub

AU - Prát, Tomáš

AU - Rydza, Nikola

AU - Rodriguez, Lesia

AU - Tan, Shutang

AU - Verstraeten, Inge

AU - Domjan, David

AU - Mazur, Ewa

AU - Smakowska-Luzan, Elwira

AU - Smet, Wouter

AU - Mor, Eliana

AU - Nolf, Jonah

AU - Yang, Bao Jun

AU - Grunewald, Wim

AU - Molnár, Gergely

AU - Belkhadir, Youssef

AU - De Rybel, Bert

AU - Friml, Jiří

N1 - Generated from Scopus record by KAUST IRTS on 2023-10-23

PY - 2020/10/30

Y1 - 2020/10/30

N2 - Spontaneously arising channels that transport the phytohormone auxin provide positional cues for selforganizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.

AB - Spontaneously arising channels that transport the phytohormone auxin provide positional cues for selforganizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.

UR - https://www.science.org/doi/10.1126/science.aba3178

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U2 - 10.1126/SCIENCE.ABA3178

DO - 10.1126/SCIENCE.ABA3178

M3 - Article

SN - 1095-9203

VL - 370

SP - 550

EP - 557

JO - SCIENCE

JF - SCIENCE

IS - 6516

ER -

Receptor kinase module targets PIN-dependent auxin transport during canalization

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