@article{628a782aa1d04f4084f8c32fa5fed86e,
title = "Regiodivergent Hydroborative Ring Opening of Epoxides via Selective C-O Bond Activation.",
abstract = "A magnesium-catalyzed regiodivergent C-O bond cleavage protocol is presented. Readily available magnesium catalysts achieve the selective hydroboration of a wide range of epoxides and oxetanes yielding secondary and tertiary alcohols in excellent yields and regioselectivities. Experimental mechanistic investigations and DFT calculations provide insight into the unexpected regiodivergence and explain the different mechanisms of the C-O bond activation and product formation.",
author = "Marc Magre and Eva Paffenholz and Bholanath Maity and Luigi Cavallo and Magnus Rueping",
note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We thank Frau Cornelia Vermeeren for preparative HPLC separation. The Deutsche Bundesstiftung Umwelt (DBU) is acknowledged for financial support for E. Paffenholz. We acknowledge the King Abdullah University of Science and Technology (KAUST) for support and the KAUST Supercomputing Laboratory for providing computational resources of the supercomputer Shaheen II.",
year = "2020",
month = jul,
day = "14",
doi = "10.1021/jacs.0c05917",
language = "English (US)",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
}