Rhenium and Manganese-Catalyzed Selective Alkenylation of Indoles

Chengming Wang, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


An efficient rhenium-catalyzed regioselective C-H bond alkenylation of indoles is reported. The protocol operates well for internal as well as terminal alkynes, affording products in good to excellent yields. Furthermore, a manganese catalyzed, acid free, regioselective C2-alkenylation of indoles with internal alkynes is described. The directing groups can be easily removed after the reaction and the resulting products can be used as valuable building blocks for the synthesis of diverse heterocyclic compounds.
Original languageEnglish (US)
Pages (from-to)2681-2685
Number of pages5
Issue number12
StatePublished - Apr 25 2018


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