TY - JOUR
T1 - Rhenium and Manganese-Catalyzed Selective Alkenylation of Indoles
AU - Wang, Chengming
AU - Rueping, Magnus
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2018/4/25
Y1 - 2018/4/25
N2 - An efficient rhenium-catalyzed regioselective C-H bond alkenylation of indoles is reported. The protocol operates well for internal as well as terminal alkynes, affording products in good to excellent yields. Furthermore, a manganese catalyzed, acid free, regioselective C2-alkenylation of indoles with internal alkynes is described. The directing groups can be easily removed after the reaction and the resulting products can be used as valuable building blocks for the synthesis of diverse heterocyclic compounds.
AB - An efficient rhenium-catalyzed regioselective C-H bond alkenylation of indoles is reported. The protocol operates well for internal as well as terminal alkynes, affording products in good to excellent yields. Furthermore, a manganese catalyzed, acid free, regioselective C2-alkenylation of indoles with internal alkynes is described. The directing groups can be easily removed after the reaction and the resulting products can be used as valuable building blocks for the synthesis of diverse heterocyclic compounds.
UR - http://hdl.handle.net/10754/627568
UR - https://onlinelibrary.wiley.com/doi/abs/10.1002/cctc.201800553
UR - http://www.scopus.com/inward/record.url?scp=85046270734&partnerID=8YFLogxK
U2 - 10.1002/cctc.201800553
DO - 10.1002/cctc.201800553
M3 - Article
SN - 1867-3880
VL - 10
SP - 2681
EP - 2685
JO - ChemCatChem
JF - ChemCatChem
IS - 12
ER -