TY - JOUR
T1 - Seed-mediated synthesis, properties and application of γ-Fe 2O3-CdSe magnetic quantum dots
AU - Lin, Alex W.H.
AU - Yen Ang, Chung
AU - Patra, Pranab K.
AU - Han, Yu
AU - Gu, Hongwei
AU - Le Breton, Jean Marie
AU - Juraszek, Jean
AU - Chiron, Hubert
AU - Papaefthymiou, Georgia C.
AU - Tamil Selvan, Subramanian
AU - Ying, Jackie Y.
N1 - Funding Information:
This work was funded by the Institute of Bioengineering and Nanotechnology (Biomedical Research Council, Agency for Science, Technology and Research, Singapore), and the National Science Foundation DMR-0604049 (at Villanova University). GCP thanks Prof. Jacques Teillet for hosting her sabbatical leave at the University of Rouen.
PY - 2011/8
Y1 - 2011/8
N2 - Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe2O3 magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.
AB - Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe2O3 magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.
KW - Magnetic quantum dots
KW - Seed-mediated growth
KW - Superparamagnetism
UR - http://www.scopus.com/inward/record.url?scp=79960697846&partnerID=8YFLogxK
U2 - 10.1016/j.jssc.2011.05.043
DO - 10.1016/j.jssc.2011.05.043
M3 - Article
AN - SCOPUS:79960697846
SN - 0022-4596
VL - 184
SP - 2150
EP - 2158
JO - Journal of Solid State Chemistry
JF - Journal of Solid State Chemistry
IS - 8
ER -
