Seed-mediated synthesis, properties and application of γ-Fe 2O3-CdSe magnetic quantum dots

Alex W.H. Lin; Chung Yen Ang; Pranab K. Patra; Yu Han; Hongwei Gu; Jean Marie Le Breton; Jean Juraszek; Hubert Chiron; Georgia C. Papaefthymiou; Subramanian Tamil Selvan; Jackie Y. Ying

doi:10.1016/j.jssc.2011.05.043

Seed-mediated synthesis, properties and application of γ-Fe ₂O₃-CdSe magnetic quantum dots

Alex W.H. Lin, Chung Yen Ang, Pranab K. Patra, Yu Han, Hongwei Gu, Jean Marie Le Breton^*, Jean Juraszek, Hubert Chiron, Georgia C. Papaefthymiou, Subramanian Tamil Selvan, Jackie Y. Ying

^*Corresponding author for this work

Physical Sciences and Engineering

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe₂O₃ magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.

Original language	English (US)
Pages (from-to)	2150-2158
Number of pages	9
Journal	Journal of Solid State Chemistry
Volume	184
Issue number	8
DOIs	https://doi.org/10.1016/j.jssc.2011.05.043
State	Published - Aug 2011

Keywords

Magnetic quantum dots
Seed-mediated growth
Superparamagnetism

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Condensed Matter Physics
Physical and Theoretical Chemistry
Inorganic Chemistry
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jssc.2011.05.043

Cite this

@article{948f0eff7a9441e8aa4455cf1ade6f8b,

title = "Seed-mediated synthesis, properties and application of γ-Fe 2O3-CdSe magnetic quantum dots",

abstract = "Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe2O3 magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.",

keywords = "Magnetic quantum dots, Seed-mediated growth, Superparamagnetism",

author = "Lin, {Alex W.H.} and {Yen Ang}, Chung and Patra, {Pranab K.} and Yu Han and Hongwei Gu and {Le Breton}, {Jean Marie} and Jean Juraszek and Hubert Chiron and Papaefthymiou, {Georgia C.} and {Tamil Selvan}, Subramanian and Ying, {Jackie Y.}",

note = "Funding Information: This work was funded by the Institute of Bioengineering and Nanotechnology (Biomedical Research Council, Agency for Science, Technology and Research, Singapore), and the National Science Foundation DMR-0604049 (at Villanova University). GCP thanks Prof. Jacques Teillet for hosting her sabbatical leave at the University of Rouen.",

year = "2011",

month = aug,

doi = "10.1016/j.jssc.2011.05.043",

language = "English (US)",

volume = "184",

pages = "2150--2158",

journal = "Journal of Solid State Chemistry",

issn = "0022-4596",

publisher = "Academic Press Inc.",

number = "8",

}

TY - JOUR

T1 - Seed-mediated synthesis, properties and application of γ-Fe 2O3-CdSe magnetic quantum dots

AU - Lin, Alex W.H.

AU - Yen Ang, Chung

AU - Patra, Pranab K.

AU - Han, Yu

AU - Gu, Hongwei

AU - Le Breton, Jean Marie

AU - Juraszek, Jean

AU - Chiron, Hubert

AU - Papaefthymiou, Georgia C.

AU - Tamil Selvan, Subramanian

AU - Ying, Jackie Y.

N1 - Funding Information: This work was funded by the Institute of Bioengineering and Nanotechnology (Biomedical Research Council, Agency for Science, Technology and Research, Singapore), and the National Science Foundation DMR-0604049 (at Villanova University). GCP thanks Prof. Jacques Teillet for hosting her sabbatical leave at the University of Rouen.

PY - 2011/8

Y1 - 2011/8

N2 - Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe2O3 magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.

AB - Seed-mediated growth of fluorescent CdSe quantum dots (QDs) around γ-Fe2O3 magnetic cores was performed at high temperature (300 °C) in the presence of organic surfactants. Bi-functional magnetic quantum dots (MQDs) with tunable emission properties were successfully prepared. The as-synthesized MQDs were characterized by high-resolution transmission electron microscopy (HRTEM) and dynamic light scattering (DLS), which confirmed the assembly of heterodimers. When a longer growth period was employed, a homogeneous dispersion of QDs around a magnetic nanoparticle was obtained. The magnetic properties of these nanocomposites were examined. The MQDs were superparamagnetic with a saturation magnetization of 0.40 emu/g and a coercivity of 138 Oe at 5 K. To demonstrate their potential application in bio-labeling, these MQDs were coated with a thin silica shell, and functionalized with a polyethylene glycol (PEG) derivative. The functionalized MQDs were effectively used for the labeling of live cell membranes of 4T1 mouse breast cancer cells and HepG2 human liver cancer cells.

KW - Magnetic quantum dots

KW - Seed-mediated growth

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