Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

P. A. T. Martins; Shahad K. Alsaiari; Khachatur Julfakyan; Z. Nie; Niveen M. Khashab

doi:10.1039/c6cc09085k

Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

P. A. T. Martins, Shahad K. Alsaiari, Khachatur Julfakyan, Z. Nie, Niveen M. Khashab

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.

Original language	English (US)
Pages (from-to)	2102-2105
Number of pages	4
Journal	Chem. Commun.
Volume	53
Issue number	13
DOIs	https://doi.org/10.1039/c6cc09085k
State	Published - 2017

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title = "Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates",

abstract = "We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.",

author = "Martins, {P. A. T.} and Alsaiari, {Shahad K.} and Khachatur Julfakyan and Z. Nie and Khashab, {Niveen M.}",

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AU - Martins, P. A. T.

AU - Alsaiari, Shahad K.

AU - Julfakyan, Khachatur

AU - Nie, Z.

AU - Khashab, Niveen M.

N1 - KAUST Repository Item: Exported on 2020-10-01

PY - 2017

Y1 - 2017

N2 - We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.

AB - We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.

UR - http://hdl.handle.net/10754/622800

UR - http://pubs.rsc.org/en/Content/ArticleLanding/2017/CC/C6CC09085K#!divAbstract

UR - http://www.scopus.com/inward/record.url?scp=85012101515&partnerID=8YFLogxK

U2 - 10.1039/c6cc09085k

DO - 10.1039/c6cc09085k

M3 - Article

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SN - 1359-7345

VL - 53

SP - 2102

EP - 2105

JO - Chem. Commun.

JF - Chem. Commun.

IS - 13

ER -

Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

Abstract

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