TY - JOUR
T1 - Self-assembly behavior of well-defined polymethylene-block-poly(ethylene glycol) copolymers in aqueous solution
AU - Alkayal, Nazeeha
AU - Zapsas, Georgios
AU - Bilalis, Panagiotis
AU - Hadjichristidis, Nikos
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Research reported in this publication supported by King Abdullah University of Science and Technology. The assistance of Dr Rachid Sougrat, KAUST Advanced Nanofabrication Imaging and Characterization Core Laboratory, in cryo-TEM experiments is gratefully acknowledged.
PY - 2016/9/22
Y1 - 2016/9/22
N2 - A series of well-defined amphiphilic polymethylene-b-poly(ethylene glycol) (PM-b-PEG) diblock copolymers, with different hydrophobic chain length, were synthesized by combining Diels-Alder reaction with polyhomologation. The successful synthetic procedure was confirmed by size-exclusion chromatography (SEC) and 1H NMR spectroscopy. These block copolymers self-assembled into spherical micelles in aqueous solutions and exhibit low critical micelle concentration (CMC) of 2–4 mg/mL, as determined by fluorescence spectroscopy using pyrene as a probe. Measurements of the micelle hydrodynamic diameters, performed by dynamic light scattering (DLS), cryo-transmission electron microscopy (cryo-TEM) and atomic force microscopy (AFM), revealed a direct dependence of the micelle size from the polymethylene block length.
AB - A series of well-defined amphiphilic polymethylene-b-poly(ethylene glycol) (PM-b-PEG) diblock copolymers, with different hydrophobic chain length, were synthesized by combining Diels-Alder reaction with polyhomologation. The successful synthetic procedure was confirmed by size-exclusion chromatography (SEC) and 1H NMR spectroscopy. These block copolymers self-assembled into spherical micelles in aqueous solutions and exhibit low critical micelle concentration (CMC) of 2–4 mg/mL, as determined by fluorescence spectroscopy using pyrene as a probe. Measurements of the micelle hydrodynamic diameters, performed by dynamic light scattering (DLS), cryo-transmission electron microscopy (cryo-TEM) and atomic force microscopy (AFM), revealed a direct dependence of the micelle size from the polymethylene block length.
UR - http://hdl.handle.net/10754/622332
UR - http://www.sciencedirect.com/science/article/pii/S0032386116308734
UR - http://www.scopus.com/inward/record.url?scp=85002142047&partnerID=8YFLogxK
U2 - 10.1016/j.polymer.2016.09.074
DO - 10.1016/j.polymer.2016.09.074
M3 - Article
SN - 0032-3861
VL - 107
SP - 415
EP - 421
JO - Polymer
JF - Polymer
ER -