Shedding light on Brønsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow

Hsuan Hung Liao; Chien Chi Hsiao; Erli Sugiono; Magnus Rueping

doi:10.1039/c3cc43996h

Shedding light on Brønsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow

Hsuan Hung Liao, Chien Chi Hsiao, Erli Sugiono, Magnus Rueping^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

A new asymmetric photocyclization–reduction cascade employing readily available aminochalcones has been developed. The reaction sequence has been achieved by unifying photochemistry and asymmetric Brønsted acid catalysis and involves photocyclization followed by Brønsted acid catalyzed enantioselective hydrogenation in batch and flow.

Original language	English (US)
Pages (from-to)	7953-7955
Number of pages	3
Journal	CHEMICAL COMMUNICATIONS
Volume	49
Issue number	72
DOIs	https://doi.org/10.1039/c3cc43996h
State	Published - Aug 13 2013
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc43996h

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title = "Shedding light on Br{\o}nsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow",

abstract = "A new asymmetric photocyclization–reduction cascade employing readily available aminochalcones has been developed. The reaction sequence has been achieved by unifying photochemistry and asymmetric Br{\o}nsted acid catalysis and involves photocyclization followed by Br{\o}nsted acid catalyzed enantioselective hydrogenation in batch and flow.",

author = "Liao, {Hsuan Hung} and Hsiao, {Chien Chi} and Erli Sugiono and Magnus Rueping",

year = "2013",

month = aug,

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doi = "10.1039/c3cc43996h",

language = "English (US)",

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journal = "CHEMICAL COMMUNICATIONS",

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Shedding light on Brønsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow. / Liao, Hsuan Hung; Hsiao, Chien Chi; Sugiono, Erli et al.
In: CHEMICAL COMMUNICATIONS, Vol. 49, No. 72, 13.08.2013, p. 7953-7955.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Shedding light on Brønsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow

AU - Liao, Hsuan Hung

AU - Hsiao, Chien Chi

AU - Sugiono, Erli

AU - Rueping, Magnus

PY - 2013/8/13

Y1 - 2013/8/13

N2 - A new asymmetric photocyclization–reduction cascade employing readily available aminochalcones has been developed. The reaction sequence has been achieved by unifying photochemistry and asymmetric Brønsted acid catalysis and involves photocyclization followed by Brønsted acid catalyzed enantioselective hydrogenation in batch and flow.

AB - A new asymmetric photocyclization–reduction cascade employing readily available aminochalcones has been developed. The reaction sequence has been achieved by unifying photochemistry and asymmetric Brønsted acid catalysis and involves photocyclization followed by Brønsted acid catalyzed enantioselective hydrogenation in batch and flow.

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U2 - 10.1039/c3cc43996h

DO - 10.1039/c3cc43996h

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AN - SCOPUS:84881596645

SN - 1359-7345

VL - 49

SP - 7953

EP - 7955

JO - CHEMICAL COMMUNICATIONS

JF - CHEMICAL COMMUNICATIONS

IS - 72

ER -

Shedding light on Brønsted acid catalysis – a photocyclization–reduction reaction for the asymmetric synthesis of tetrahydroquinolines from aminochalcones in batch and flow

Abstract

ASJC Scopus subject areas

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