TY - JOUR
T1 - Spread-Spectrum Modulated Multi-Channel Biosignal Acquisition Using a Shared Analog CMOS Front-End
AU - Rout, Samprajani
AU - Monna, Bert
AU - Pareschi, Fabio
AU - Setti, Gianluca
AU - Serdijn, Wouter A.
N1 - KAUST Repository Item: Exported on 2023-09-30
Acknowledgements: The authors would like to acknowledge the support and funding from NWO and the Dutch Heart Foundation (Project number: 14728). The authors wish to thank Prof. Earl McCune for his contributions in the early stage of this work. The authors would like to thank Prof. Natasja de Groot from Erasmus Medical Centre, Rotterdam for providing the invasively acquired AEGs.
PY - 2023/9/19
Y1 - 2023/9/19
N2 - The key challenges in designing a multi-channel biosignal acquisition system for an ambulatory or invasive medical application with a high channel count are reducing the power consumption, area consumption and the outgoing wire count. This paper proposes a spread-spectrum modulated biosignal acquisition system using a shared amplifier and an analog-to-digital converter (ADC). We propose a design method to optimize a recording system for a given application based on the required SNR performance, number of inputs, and area. The proposed method is tested and validated on real pre-recorded atrial electrograms and achieves an average percentage root- mean-square difference (PRD) performance of 2.65% and 3.02% for sinus rhythm (SR) and atrial fibrillation (AF), respectively by using pseudo-random binary-sequence (PRBS) codes with a code-length of 511, for 16 inputs. We implement a 4-input spread-spectrum analog front-end in a 0.18μm CMOS process to demonstrate the proposed approach. The analog front-end consists of a shared amplifier, a 2nd order ΣΔ ADC sampled at 7.8MHz , used for digitization, and an on-chip 7-bit PRBS generator. It achieves a number-of-inputs to outgoing-wire ratio of 4:1 while consuming 23μA /input including biasing from a 1.8V power supply and 0.067mm2 in area.
AB - The key challenges in designing a multi-channel biosignal acquisition system for an ambulatory or invasive medical application with a high channel count are reducing the power consumption, area consumption and the outgoing wire count. This paper proposes a spread-spectrum modulated biosignal acquisition system using a shared amplifier and an analog-to-digital converter (ADC). We propose a design method to optimize a recording system for a given application based on the required SNR performance, number of inputs, and area. The proposed method is tested and validated on real pre-recorded atrial electrograms and achieves an average percentage root- mean-square difference (PRD) performance of 2.65% and 3.02% for sinus rhythm (SR) and atrial fibrillation (AF), respectively by using pseudo-random binary-sequence (PRBS) codes with a code-length of 511, for 16 inputs. We implement a 4-input spread-spectrum analog front-end in a 0.18μm CMOS process to demonstrate the proposed approach. The analog front-end consists of a shared amplifier, a 2nd order ΣΔ ADC sampled at 7.8MHz , used for digitization, and an on-chip 7-bit PRBS generator. It achieves a number-of-inputs to outgoing-wire ratio of 4:1 while consuming 23μA /input including biasing from a 1.8V power supply and 0.067mm2 in area.
UR - http://hdl.handle.net/10754/694697
UR - https://ieeexplore.ieee.org/document/10255273/
U2 - 10.1109/tbcas.2023.3317188
DO - 10.1109/tbcas.2023.3317188
M3 - Article
SN - 1932-4545
SP - 1
EP - 13
JO - IEEE Transactions on Biomedical Circuits and Systems
JF - IEEE Transactions on Biomedical Circuits and Systems
ER -