Study of sample dispersion mechanisms in an electroosmotically pumped microchannel

B. Debusschere; H. Najm; A. Matta; O. Knio; R. Ghanem; O. Le Maître

Study of sample dispersion mechanisms in an electroosmotically pumped microchannel

B. Debusschere^*, H. Najm, A. Matta, O. Knio, R. Ghanem, O. Le Maître

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

This paper presents detailed simulations of electroosmotic microchannel flow to study the effect of species charge, chemical reaction and random ζ potential variability on both elektrokinetic and hydrodynamic dispersion. The physical model used accounts for the coupled nature of momentum, species transport and reactions, as well as the electrostatic field. The chemistry model accounts for pH-dependent protein labeling reactions as well as detailed buffer electrochemistry. Using polynomical chaos expansions, the model also accounts for stochastic ζ potential variability due to heterogeneous wall surface properties. The results show that dispersion increases for higher species charges and for larger variability in ζ. The dispersion also depends mildly on the correlation length of the ζ potential variability.

Original language	English (US)
Title of host publication	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Editors	M. Laudon, B. Romanowicz
Pages	154-157
Number of pages	4
State	Published - 2003
Externally published	Yes
Event	2003 Nanotechnology Conference and Trade Show - Nanotech 2003 - San Francisco, CA, United States Duration: Feb 23 2003 → Feb 27 2003

Publication series

Name	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Volume	1

Other

Other	2003 Nanotechnology Conference and Trade Show - Nanotech 2003
Country/Territory	United States
City	San Francisco, CA
Period	02/23/03 → 02/27/03

Keywords

Labeling
Microchannel
Polynomial chaos
Sample dispersion
Simulation

ASJC Scopus subject areas

General Engineering

Cite this

@inproceedings{d44699e235a1485387558d350ad6c3b2,

title = "Study of sample dispersion mechanisms in an electroosmotically pumped microchannel",

abstract = "This paper presents detailed simulations of electroosmotic microchannel flow to study the effect of species charge, chemical reaction and random ζ potential variability on both elektrokinetic and hydrodynamic dispersion. The physical model used accounts for the coupled nature of momentum, species transport and reactions, as well as the electrostatic field. The chemistry model accounts for pH-dependent protein labeling reactions as well as detailed buffer electrochemistry. Using polynomical chaos expansions, the model also accounts for stochastic ζ potential variability due to heterogeneous wall surface properties. The results show that dispersion increases for higher species charges and for larger variability in ζ. The dispersion also depends mildly on the correlation length of the ζ potential variability.",

keywords = "Labeling, Microchannel, Polynomial chaos, Sample dispersion, Simulation",

author = "B. Debusschere and H. Najm and A. Matta and O. Knio and R. Ghanem and {Le Ma{\^i}tre}, O.",

year = "2003",

language = "English (US)",

isbn = "0972842209",

series = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003",

pages = "154--157",

editor = "M. Laudon and B. Romanowicz",

booktitle = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003",

note = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003 ; Conference date: 23-02-2003 Through 27-02-2003",

}

Debusschere, B, Najm, H, Matta, A, Knio, O, Ghanem, R & Le Maître, O 2003, Study of sample dispersion mechanisms in an electroosmotically pumped microchannel. in M Laudon & B Romanowicz (eds), 2003 Nanotechnology Conference and Trade Show - Nanotech 2003. 2003 Nanotechnology Conference and Trade Show - Nanotech 2003, vol. 1, pp. 154-157, 2003 Nanotechnology Conference and Trade Show - Nanotech 2003, San Francisco, CA, United States, 02/23/03.

Study of sample dispersion mechanisms in an electroosmotically pumped microchannel. / Debusschere, B.; Najm, H.; Matta, A. et al.
2003 Nanotechnology Conference and Trade Show - Nanotech 2003. ed. / M. Laudon; B. Romanowicz. 2003. p. 154-157 (2003 Nanotechnology Conference and Trade Show - Nanotech 2003; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Study of sample dispersion mechanisms in an electroosmotically pumped microchannel

AU - Debusschere, B.

AU - Najm, H.

AU - Matta, A.

AU - Knio, O.

AU - Ghanem, R.

AU - Le Maître, O.

PY - 2003

Y1 - 2003

N2 - This paper presents detailed simulations of electroosmotic microchannel flow to study the effect of species charge, chemical reaction and random ζ potential variability on both elektrokinetic and hydrodynamic dispersion. The physical model used accounts for the coupled nature of momentum, species transport and reactions, as well as the electrostatic field. The chemistry model accounts for pH-dependent protein labeling reactions as well as detailed buffer electrochemistry. Using polynomical chaos expansions, the model also accounts for stochastic ζ potential variability due to heterogeneous wall surface properties. The results show that dispersion increases for higher species charges and for larger variability in ζ. The dispersion also depends mildly on the correlation length of the ζ potential variability.

AB - This paper presents detailed simulations of electroosmotic microchannel flow to study the effect of species charge, chemical reaction and random ζ potential variability on both elektrokinetic and hydrodynamic dispersion. The physical model used accounts for the coupled nature of momentum, species transport and reactions, as well as the electrostatic field. The chemistry model accounts for pH-dependent protein labeling reactions as well as detailed buffer electrochemistry. Using polynomical chaos expansions, the model also accounts for stochastic ζ potential variability due to heterogeneous wall surface properties. The results show that dispersion increases for higher species charges and for larger variability in ζ. The dispersion also depends mildly on the correlation length of the ζ potential variability.

KW - Labeling

KW - Microchannel

KW - Polynomial chaos

KW - Sample dispersion

KW - Simulation

UR - http://www.scopus.com/inward/record.url?scp=1842523727&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:1842523727

SN - 0972842209

SN - 9780972842204

T3 - 2003 Nanotechnology Conference and Trade Show - Nanotech 2003

SP - 154

EP - 157

BT - 2003 Nanotechnology Conference and Trade Show - Nanotech 2003

A2 - Laudon, M.

A2 - Romanowicz, B.

T2 - 2003 Nanotechnology Conference and Trade Show - Nanotech 2003

Y2 - 23 February 2003 through 27 February 2003

ER -

Study of sample dispersion mechanisms in an electroosmotically pumped microchannel

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

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Cite this