Superhydrophobicity, plasmonics and Raman spectroscopy for few/single molecule detection down to attomolar concentration

Gobind Das, F. Gentile, F. De Angelis, M. L. Coluccio, Carlo Liberale, R. Proietti Zaccaria, Enzo Di Fabrizio*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations


Few/single molecule detection is of great importance in fields including biomedicine, safety and eco-pollution in relation to rare and dangerous chemicals. Superhydrophobic surfaces incorporated with the nanoplasmonic structure enable this device to overcome the diffusion limit of molecules dissolved in water with the concentration down to 10 attomolar. In this paper demonstrated the fabrication of hydrophobic surfaces using optical lithography/reactive ion etching and its application to overcome the diffusion limit. Various experiments such as contact angle measurements, SEM, fluorescence, Raman and FTIR absorption spectroscopy were performed which indicate that utilizing this device it could be possible to perform the measurements for the sample with extremely low dilution. The major application of this novel family of devices would be the early detection of tumors or other important pathologies, with incredible advances in medicine.

Original languageEnglish (US)
Title of host publicationPlasmonics
Subtitle of host publicationMetallic Nanostructures and Their Optical Properties X
StatePublished - Dec 1 2012
EventPlasmonics: Metallic Nanostructures and Their Optical Properties X - San Diego, CA, United States
Duration: Aug 12 2012Aug 16 2012

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherPlasmonics: Metallic Nanostructures and Their Optical Properties X
Country/TerritoryUnited States
CitySan Diego, CA


  • FTIR absorption spectroscopy
  • Plasmonics
  • Superhydrophobic surfaces
  • Surface enhanced raman scattering

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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