Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal

Valérie Gertosio, Catherine C. Santini*, Jean Marie Basset, François Bayard, Michel Vivat, Jean Buendia

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The synthesis of a new progestomimetic steroid, analogous to the cetaloxopromegestone precursor of Trimegestone has been carried out in eight steps from 9α-hydroxyandrost-4-ene-3,17-dione. This latter compound can be obtained from the fermentation of γ-sitosterol, a sterol extracted from soya bean oil.

Original languageEnglish (US)
Pages (from-to)1521-1525
Number of pages5
JournalEuropean Journal of Organic Chemistry
Issue number8
StatePublished - Apr 2000
Externally publishedYes


  • Ketones
  • Steroids
  • Synthetic methods

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry


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