Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes

Andrea Aramini; Maria C. Cesta; Silvia Coniglio; Christian Bijani; Sandro Colagioia; Valerio D'Elia; Marcello Allegretti

doi:10.1021/jo034770f

Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes

Andrea Aramini^*, Maria C. Cesta, Silvia Coniglio, Christian Bijani, Sandro Colagioia, Valerio D'Elia, Marcello Allegretti

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.

Original language	English (US)
Pages (from-to)	7911-7914
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	68
Issue number	20
DOIs	https://doi.org/10.1021/jo034770f
State	Published - Oct 3 2003
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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title = "Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes",

abstract = "The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.",

author = "Andrea Aramini and Cesta, {Maria C.} and Silvia Coniglio and Christian Bijani and Sandro Colagioia and Valerio D'Elia and Marcello Allegretti",

year = "2003",

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language = "English (US)",

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TY - JOUR

T1 - Synthesis of E-aryl ethenesulfonamides

T2 - A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes

AU - Aramini, Andrea

AU - Cesta, Maria C.

AU - Coniglio, Silvia

AU - Bijani, Christian

AU - Colagioia, Sandro

AU - D'Elia, Valerio

AU - Allegretti, Marcello

PY - 2003/10/3

Y1 - 2003/10/3

N2 - The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.

AB - The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.

UR - http://www.scopus.com/inward/record.url?scp=0141431031&partnerID=8YFLogxK

U2 - 10.1021/jo034770f

DO - 10.1021/jo034770f

M3 - Article

C2 - 14510579

AN - SCOPUS:0141431031

SN - 0022-3263

VL - 68

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EP - 7914

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 20

ER -

Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes

Abstract

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