TY - JOUR
T1 - Synthesis of reduced-size gold nanostars and internalization in SH-SY5Y cells
AU - Dacarro, Giacomo
AU - Pallavicini, Piersandro
AU - Bertani, Serena Maria
AU - Chirico, Giuseppe
AU - D'Alfonso, Laura
AU - Falqui, Andrea
AU - Marchesi, Nicoletta
AU - Pascale, Alessia
AU - Sironi, Laura
AU - Taglietti, Angelo
AU - Zuddas, Efisio
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work was supported by the Italian Ministry of Instruction, University and Research (MIUR) and by PRIN 2010–11 [20109PLMH2]. The University of Pavia and CIRCMSB (Consorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici) are also gratefully acknowledged for support. LD would like to thank Sara Oprandi for her help in collecting the photothermal response data.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - The synthesis of large pentatwinned five-branched gold nanostars (GNS) has been modified so to obtain overall dimensions shrunk to 60% and a lower branches aspect ratio, leading to a dramatic blue shift of their two near-infrared (NIR) localized surface plasmon resonances (LSPR) absorptions but still maintaining one LSPR in the biotransparent NIR range. The interactions of polyethylene glycol (PEG) coated large and shrunk GNS with SH-SY5Y cells revealed that the large ones (DCI - diameter of the circumference in which GNS can be inscribed = 76 nm) are internalized more efficiently than the shrunk ones (DCI = 46 nm), correlating with a decreased cells surving fraction.
AB - The synthesis of large pentatwinned five-branched gold nanostars (GNS) has been modified so to obtain overall dimensions shrunk to 60% and a lower branches aspect ratio, leading to a dramatic blue shift of their two near-infrared (NIR) localized surface plasmon resonances (LSPR) absorptions but still maintaining one LSPR in the biotransparent NIR range. The interactions of polyethylene glycol (PEG) coated large and shrunk GNS with SH-SY5Y cells revealed that the large ones (DCI - diameter of the circumference in which GNS can be inscribed = 76 nm) are internalized more efficiently than the shrunk ones (DCI = 46 nm), correlating with a decreased cells surving fraction.
UR - http://hdl.handle.net/10754/625151
UR - http://www.sciencedirect.com/science/article/pii/S0021979717307671
UR - http://www.scopus.com/inward/record.url?scp=85021793329&partnerID=8YFLogxK
U2 - 10.1016/j.jcis.2017.06.102
DO - 10.1016/j.jcis.2017.06.102
M3 - Article
C2 - 28697545
SN - 0021-9797
VL - 505
SP - 1055
EP - 1064
JO - Journal of Colloid and Interface Science
JF - Journal of Colloid and Interface Science
ER -