TY - JOUR
T1 - Synthetic Biology Open Language (SBOL) Version 2.1.0
AU - Beal, Jacob
AU - Cox, Robert Sidney
AU - Grunberg, Raik
AU - McLaughlin, James
AU - Nguyen, Tramy
AU - Bartley, Bryan
AU - Bissell, Michael
AU - Choi, Kiri
AU - Clancy, Kevin
AU - Macklin, Chris
AU - Madsen, Curtis
AU - Misirli, Goksel
AU - Oberortner, Ernst
AU - Pocock, Matthew
AU - Roehner, Nicholas
AU - Samineni, Meher
AU - Zhang, Michael
AU - Zhang, Zhen
AU - Zundel, Zach
AU - Gennari, John H.
AU - Myers, Chris
AU - Sauro, Herbert
AU - Wipat, Anil
N1 - KAUST Repository Item: Exported on 2021-03-05
PY - 2016/9/1
Y1 - 2016/9/1
N2 - SummarySynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.1 of SBOL that builds upon version 2.0 published in last year’s JIB special issue. In particular, SBOL 2.1 includes improved rules for what constitutes a valid SBOL document, new role fields to simplify the expression of sequence features and how components are used in context, and new best practices descriptions to improve the exchange of basic sequence topology information and the description of genetic design provenance, as well as miscellaneous other minor improvements.
AB - SummarySynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.1 of SBOL that builds upon version 2.0 published in last year’s JIB special issue. In particular, SBOL 2.1 includes improved rules for what constitutes a valid SBOL document, new role fields to simplify the expression of sequence features and how components are used in context, and new best practices descriptions to improve the exchange of basic sequence topology information and the description of genetic design provenance, as well as miscellaneous other minor improvements.
UR - http://hdl.handle.net/10754/667835
UR - http://www.degruyter.com/view/j/jib.2016.13.issue-3/jib-2016-291/jib-2016-291.xml
UR - http://www.scopus.com/inward/record.url?scp=85041252119&partnerID=8YFLogxK
U2 - 10.1515/jib-2016-291
DO - 10.1515/jib-2016-291
M3 - Article
SN - 1613-4516
VL - 13
SP - 30
EP - 132
JO - Journal of integrative bioinformatics
JF - Journal of integrative bioinformatics
IS - 3
ER -