Abstract
The bithorax (BX) complex of Drosophila is a complex polygenic region with a multifactorial system of regulation. One of the levels of the regulatory system of the BX complex is its association with the nuclear skeleton structures through a specific interaction of the M/SAR DNA with the nuclear matrix proteins. In the present work, M/SAR elements were mapped on the molecular-genetic map of the region. All of the elements examined were found to colocalize with regulatory elements and form clusters that restrict/bracket the genetically active domains. All M/SAR DNA revealed was shown to bins specifically to the purified Drosophila melanogaster lamin.
Original language | English (US) |
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Pages (from-to) | 1206-1216 |
Number of pages | 11 |
Journal | Russian Journal of Genetics |
Volume | 41 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2005 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics