The M/SAR elements of the bithorax complex in Drosophila melanogaster

T. V. Boykova; V. Orlando; R. Lpo; S. S. Bogachev

The M/SAR elements of the bithorax complex in Drosophila melanogaster

T. V. Boykova, V. Orlando, R. Lpo, S. S. Bogachev

Research output: Contribution to journal › Article › peer-review

Abstract

The bithorax (BX) complex of Drosophila is a complex polygenic region with a multifactorial system of regulation. One of the levels of the regulatory system of the BX complex is its association with the nuclear skeleton structures through a specific interaction of the M/SAR DNA with the nuclear matrix proteins. In the present work, M/SAR elements were mapped on the molecular-genetic map of the region. All of the elements examined were found to colocalize with regulatory elements and form clusters that restrict/bracket the genetically active domains. All M/SAR DNA revealed was shown to bins specifically to the purified Drosophila melanogaster lamin.

Original language	English (US)
Pages (from-to)	1467-1479
Number of pages	13
Journal	Genetika
Volume	41
Issue number	11
State	Published - 2005
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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AU - Orlando, V.

AU - Lpo, R.

AU - Bogachev, S. S.

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AB - The bithorax (BX) complex of Drosophila is a complex polygenic region with a multifactorial system of regulation. One of the levels of the regulatory system of the BX complex is its association with the nuclear skeleton structures through a specific interaction of the M/SAR DNA with the nuclear matrix proteins. In the present work, M/SAR elements were mapped on the molecular-genetic map of the region. All of the elements examined were found to colocalize with regulatory elements and form clusters that restrict/bracket the genetically active domains. All M/SAR DNA revealed was shown to bins specifically to the purified Drosophila melanogaster lamin.

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AN - SCOPUS:33644819579

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JO - Genetika

JF - Genetika

IS - 11

ER -

The M/SAR elements of the bithorax complex in Drosophila melanogaster

Abstract

ASJC Scopus subject areas

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