The origin and evolution of human T-cell lymphotropic virus types I and II

Yoshiyuki Suzuki, Takashi Gojobori*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

Studies on human T-cell lymphotropic virus types I (HTLV-I) and II (HTLV-II) are briefly reviewed from the viewpoint of molecular evolution, with special reference to the evolutionary rate and evolutionary relationships among these viruses. In particular, it appears that, in contrast to the low level of variability of HTLV-I among different isolates, individual isolates form quasispecies structures. Elucidating the mechanisms connecting these two phenomena will be one of the future problems in the study of the molecular evolution of HTLV-I and HTLV-II.

Original languageEnglish (US)
Pages (from-to)69-84
Number of pages16
JournalVirus Genes
Volume16
Issue number1
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • Evolutionary rate
  • Genetic variation
  • Geographical distribution
  • Human T-cell lymphotropic virus
  • Molecular evolution
  • Phylogenetic tree

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Virology

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