Transgenerational adaptation to ocean acidification determines the susceptibility of filter-feeding rotifers to nanoplastics.

Min-Sub Kim, Young Hwan Lee, Yoseop Lee, Eunjin Byeon, Duck-Hyun Kim, Minghua Wang, Atsushi Hagiwara, Manuel Aranda, Rudolf Shiu Sun Wu, Heum Gi Park, Jae-Seong Lee

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The adaptation of marine organisms to the impending challenges presented by ocean acidification (OA) is essential for their future survival, and mechanisms underlying OA adaptation have been reported in several marine organisms. In the natural environment, however, marine organisms are often exposed to a combination of environmental stressors, and the interactions between adaptive responses have yet to be elucidated. Here, we investigated the susceptibility of filter-feeding rotifers to short-term (ST) and long-term (LT) (≥180 generations) high CO2 conditions coupled with nanoplastic (NPs) exposure (ST+ and LT+). Adaptation of rotifers to elevated CO2 caused differences in ingestion and accumulation of NPs, resulting in a significantly different mode of action on in vivo endpoints between the ST+ and LT+ groups. Moreover, microRNA-mediated epigenetic regulation was strongly correlated with the varied adaptive responses between the ST+ and LT+ groups, revealing novel regulatory targets and pathways. Our results indicate that pre-exposure history to increased CO2 levels is an important factor in the susceptibility of rotifers to NPs.
Original languageEnglish (US)
Pages (from-to)132593
JournalJournal of hazardous materials
Volume461
DOIs
StatePublished - Sep 28 2023

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Environmental Engineering
  • Health, Toxicology and Mutagenesis
  • Waste Management and Disposal

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