Tunable mechanical properties of ultrasmall peptide hydrogels by crosslinking and functionalization to achieve the 3D distribution of cells

Wei Yang Seow; Charlotte A.E. Hauser

doi:10.1002/adhm.201200463

Tunable mechanical properties of ultrasmall peptide hydrogels by crosslinking and functionalization to achieve the 3D distribution of cells

Wei Yang Seow, Charlotte A.E. Hauser^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

A disulfide-crosslinked hydrogel made from ultrasmall peptides is introduced. Crosslinked gels are more elastic and better able to maintain shape integrity. Using facile chemistry, RGD (or other bioactive signals) can be conjugated onto the peptide fibers. Gels formed are biocompatible and support the three-dimensional distribution of cells.

Original language	English (US)
Pages (from-to)	1219-1223
Number of pages	5
Journal	Advanced healthcare materials
Volume	2
Issue number	9
DOIs	https://doi.org/10.1002/adhm.201200463
State	Published - Sep 2013
Externally published	Yes

Keywords

3D environment
Crosslinking
Disulfide bonds
Hydrogel
Ultrasmall peptides

ASJC Scopus subject areas

Biomedical Engineering
Biomaterials
Pharmaceutical Science

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10.1002/adhm.201200463

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abstract = "A disulfide-crosslinked hydrogel made from ultrasmall peptides is introduced. Crosslinked gels are more elastic and better able to maintain shape integrity. Using facile chemistry, RGD (or other bioactive signals) can be conjugated onto the peptide fibers. Gels formed are biocompatible and support the three-dimensional distribution of cells.",

keywords = "3D environment, Crosslinking, Disulfide bonds, Hydrogel, Ultrasmall peptides",

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year = "2013",

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AU - Hauser, Charlotte A.E.

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AB - A disulfide-crosslinked hydrogel made from ultrasmall peptides is introduced. Crosslinked gels are more elastic and better able to maintain shape integrity. Using facile chemistry, RGD (or other bioactive signals) can be conjugated onto the peptide fibers. Gels formed are biocompatible and support the three-dimensional distribution of cells.

KW - 3D environment

KW - Crosslinking

KW - Disulfide bonds

KW - Hydrogel

KW - Ultrasmall peptides

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M3 - Article

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Tunable mechanical properties of ultrasmall peptide hydrogels by crosslinking and functionalization to achieve the 3D distribution of cells

Abstract

Keywords

ASJC Scopus subject areas

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