VIP neurons in the cerebral cortex

Pierre J. Magistretti*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

69 Scopus citations


VIP-containing cells in the neocortex are intrinsic neurons of the bipolar type, which release VIP through mechanisms that involve Ca2+ and lipoxygenase metabolites. VIP receptors are coupled to cAMP-generating systems that are amplified by various neurotransmitters such as noradrenaline, histamine and GABA. Pierre Magistretti reviews the evidence that VIP neurons play an important role in the local regulation of metabolism in the cerebral cortex by stimulating glycogenolysis and altering cortical blood flow.

Original languageEnglish (US)
Pages (from-to)250-254
Number of pages5
JournalTrends in Pharmacological Sciences
Issue number6
StatePublished - Jun 1990
Externally publishedYes

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology


Dive into the research topics of 'VIP neurons in the cerebral cortex'. Together they form a unique fingerprint.

Cite this