Visible-light photoredox-catalyzed synthesis of nitrones: Unexpected rate acceleration by water in the synthesis of isoxazolidines

Hong Hou; Shaoqun Zhu; Fangfang Pan; Magnus Rueping

doi:10.1021/ol500893g

Visible-light photoredox-catalyzed synthesis of nitrones: Unexpected rate acceleration by water in the synthesis of isoxazolidines

Hong Hou, Shaoqun Zhu, Fangfang Pan, Magnus Rueping^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

A new oxidative [3 + 2] cycloaddition of N-substituted hydroxylamines with alkenes was established under visible light photoredox catalysis. This novel protocol provides a rapid, mild, and efficient access to valuable five-membered ring isoxazolidine heterocycles in a concise fashion.

Original language	English (US)
Pages (from-to)	2872-2875
Number of pages	4
Journal	Organic Letters
Volume	16
Issue number	11
DOIs	https://doi.org/10.1021/ol500893g
State	Published - Jun 6 2014
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol500893g

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title = "Visible-light photoredox-catalyzed synthesis of nitrones: Unexpected rate acceleration by water in the synthesis of isoxazolidines",

abstract = "A new oxidative [3 + 2] cycloaddition of N-substituted hydroxylamines with alkenes was established under visible light photoredox catalysis. This novel protocol provides a rapid, mild, and efficient access to valuable five-membered ring isoxazolidine heterocycles in a concise fashion.",

author = "Hong Hou and Shaoqun Zhu and Fangfang Pan and Magnus Rueping",

year = "2014",

month = jun,

day = "6",

doi = "10.1021/ol500893g",

language = "English (US)",

volume = "16",

pages = "2872--2875",

journal = "Organic Letters",

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T1 - Visible-light photoredox-catalyzed synthesis of nitrones

T2 - Unexpected rate acceleration by water in the synthesis of isoxazolidines

AU - Hou, Hong

AU - Zhu, Shaoqun

AU - Pan, Fangfang

AU - Rueping, Magnus

PY - 2014/6/6

Y1 - 2014/6/6

N2 - A new oxidative [3 + 2] cycloaddition of N-substituted hydroxylamines with alkenes was established under visible light photoredox catalysis. This novel protocol provides a rapid, mild, and efficient access to valuable five-membered ring isoxazolidine heterocycles in a concise fashion.

AB - A new oxidative [3 + 2] cycloaddition of N-substituted hydroxylamines with alkenes was established under visible light photoredox catalysis. This novel protocol provides a rapid, mild, and efficient access to valuable five-membered ring isoxazolidine heterocycles in a concise fashion.

UR - http://www.scopus.com/inward/record.url?scp=84902096261&partnerID=8YFLogxK

U2 - 10.1021/ol500893g

DO - 10.1021/ol500893g

M3 - Article

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AN - SCOPUS:84902096261

SN - 1523-7060

VL - 16

SP - 2872

EP - 2875

JO - Organic Letters

JF - Organic Letters

IS - 11

ER -

Visible-light photoredox-catalyzed synthesis of nitrones: Unexpected rate acceleration by water in the synthesis of isoxazolidines

Abstract

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