Well-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromides

Ronglu Huang, Yangjie Huang, Xiaoxi Lin, Mingguang Rong, Zhiqiang Weng

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Copper(I) fluoroalkoxide complexes bearing dinitrogen ligands were synthesized and the structure and reactivity of the complexes toward trifluoroethoxylation, pentafluoropropoxylation, and tetrafluoropropoxylation of aryl and heteroaryl bromides were investigated. Efficiency drive: A series of copper(I) fluoroalkoxide complexes bearing N,N ligands have been prepared and structurally characterized. These well-defined complexes serve as efficient reagents for the fluoroalkoxylation of aryl and heteroaryl bromides to produce a wide range of trifluoroethyl, pentafluoropropyl, and tetrafluoropropyl (hetero)aryl ethers in good to excellent yields.
Original languageEnglish (US)
Pages (from-to)5736-5739
Number of pages4
JournalAngewandte Chemie International Edition
Volume54
Issue number19
DOIs
StatePublished - Mar 17 2015
Externally publishedYes

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