Worming toward Transdifferentiation, One (Epigenetic) Step at a Time

Ergin Beyret, Juan Carlos s.Izpisua Belmonte*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations


Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.

Original languageEnglish (US)
Pages (from-to)641-642
Number of pages2
JournalDevelopmental Cell
Issue number6
StatePublished - Sep 29 2014
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • General Biochemistry, Genetics and Molecular Biology
  • Developmental Biology
  • Cell Biology


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