Worming toward Transdifferentiation, One (Epigenetic) Step at a Time

Ergin Beyret; Juan Carlos s.Izpisua Belmonte

doi:10.1016/j.devcel.2014.09.003

Worming toward Transdifferentiation, One (Epigenetic) Step at a Time

Ergin Beyret, Juan Carlos s.Izpisua Belmonte^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.

Original language	English (US)
Pages (from-to)	641-642
Number of pages	2
Journal	Developmental Cell
Volume	30
Issue number	6
DOIs	https://doi.org/10.1016/j.devcel.2014.09.003
State	Published - Sep 29 2014
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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10.1016/j.devcel.2014.09.003

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title = "Worming toward Transdifferentiation, One (Epigenetic) Step at a Time",

abstract = "Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.",

author = "Ergin Beyret and Belmonte, {Juan Carlos s.Izpisua}",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier Inc.",

year = "2014",

month = sep,

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doi = "10.1016/j.devcel.2014.09.003",

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AU - Beyret, Ergin

AU - Belmonte, Juan Carlos s.Izpisua

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Y1 - 2014/9/29

N2 - Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.

AB - Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.

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U2 - 10.1016/j.devcel.2014.09.003

DO - 10.1016/j.devcel.2014.09.003

M3 - Short survey

C2 - 25268170

AN - SCOPUS:84908221483

SN - 1534-5807

VL - 30

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EP - 642

JO - Developmental Cell

JF - Developmental Cell

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Worming toward Transdifferentiation, One (Epigenetic) Step at a Time

Abstract

ASJC Scopus subject areas

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